Gene l0017 encodes a second chaperone for EspA of enterohaemorrhagic Escherichia coli O157 : H7
نویسندگان
چکیده
منابع مشابه
Surveillance of enterohaemorrhagic Escherichia coli O157:H7 in southern Thailand.
In recent years, several studies have reported infections associated with Escherichia coli O157:H7, especially in developed countries (1). Except Japan, isolation of E. coli O157:H7 has also been reported in Asian countries (2). Limited work has been carried out on E. coli O157:H7 in Thailand (3,4). Suthienkul et al. reported no E. coli O157 in retail meat and cattle (3), but it was recently is...
متن کاملEffective medicinal plants against enterohaemorrhagic Escherichia coli O157:H7.
The stimulating effect of subinhibitory concentrations of antibiotics on the production of verocytotoxin (VT) by enterohaemorrhagic Escherichia coli (EHEC) O157:H7 has been claimed. The purpose of this study was to find an alternative, but bioactive medicine for the treatment of this organism. Fifty-eight preparations of aqueous and ethanolic extracts of 38 medicinal plant species commonly used...
متن کاملA DNA Vaccine against Escherichia coli O157:H7
Background: Infection with Escherichia coli O157:H7 rarely leads to bloody diarrhea and causes hemolytic uremic syndrome with renal failure that can be deadly dangerous. Intimin, translocated Intimin receptor (Tir), and enterohemorrhagic E. coli (EHEC) secreted protein A (EspA) proteins are the virulence factors expressed by locus of enterocyte effacement locus of EHEC. This bacterium needs Es...
متن کاملEspA-Intimin chimeric protein, a candidate vaccine against Escherichia coli O157:H7
BACKGROUND AND OBJECTIVE Enterohemorrhagic Escherichia coli (EHEC) O157:H7 is an important enteric pathogen in human causing bloody or nonbloody diarrhea, which may be complicated by hemolytic uremic syndrome (HUS). Cattle are an important reservoir of EHEC. This research aims at vaccination with a divalent chimer protein composed of EspA120 and Intimin 282 and its preventive effect of EHEC O15...
متن کاملIsolation of recombinant antibodies against EspA and intimin of Escherichia coli O157:H7.
Intimin, Tir, and EspA proteins are expressed by attaching-effacing Escherichia coli, which include enteropathogenic and enterohemorrhagic E. coli pathotypes. EspA proteins are part of the type three secretion system needle complex that delivers Tir to the host epithelial cell, while surface arrayed intimin docks the bacterium to the translocated Tir. This intimate attachment leads to attaching...
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ژورنال
عنوان ژورنال: Microbiology
سال: 2008
ISSN: 1350-0872,1465-2080
DOI: 10.1099/mic.0.2007/013946-0